I agree about being asked a question as an introduction, as opposed to just saying 'Hi' etc..
Being asked a sensible question regarding my avatar or what she is wearing will almost always garner a positive response from me.
Second life is not real life and the differences and nuances when introducing yourself are not necessarily the same.
Just because someone comes and stands in front of you does not automatically mean you can see them. I'm often camming in stores or events and not looking at myself and I don't want to lose my cam position just to see who it is. I may read their profile but if it was sensibl conversation starter I may just start chatting without ever looking at them and then like them regardless of their avatar appearance.
If I like a man's avatar I will almost always talk to him. These men are rarely the smooth, sleek, polished and modern avatars, but rather the ones I simply like the look of. Often they are the classic system avatars because to achieve a decent mature male look is not easy with mesha body and face. I like older men in RL too, so it's how I am.
I feel for men sometimes as the onus is often on them to make the first move, so when I make the first move they are often flattered, but not always. I get the occasional kick-back too and it's a shame when he has an avatar I really like.
The division between real life and 2nd life is a very easy one for me to make. Even while Firestorm is loading I am already becoming 'me'.. and me is my SL avatar. I'm not interested in the person's real life at all, any relationship is between our two avatars.
RL questions, even as basic as 'which country are you from', are off-putting for me. My avatar is what you see, my personality is my avatar. Take it or leave it.