Krystina Ferraris

Wait Maddie you’ll probably win... you’ll set me on fire 🔥

I need infinite length telomeres or at least telomeres that don’t wear down 👌

Over here (Pre-Covid when night life was still happening) A&Es on weekends were full of women assaulted by men in public places, not restrooms. There were also a crazy number of women who were assaulted by other women in restrooms. I am not denying that the situation you describe can happen. I would be interested in knowing how many times that actually happened? A horny and possibly drunk guy can wander into a women's bathroom without pretending to be a transgender woman, and do whatever is in his head at that particular time. Looking at the average toilet cubicle out there though, I'm thinking the guy wanting to take a peek at my privates must be quite the contortionist to fold under the door, or quite the gymnast to suspend himself over the walls. There are many facets to this, as someone else mentioned earlier for example some cultures would not accept unisex toilets due to religious belief or other cultural factors.

I honestly can't understand this... I see people for who they are, they go to the restroom they choose as the gender they present. Really who cares? There is no choosing, I don't "choose" to go the female toilet, that's how I was born and what I see fit. Women of all genders should not "choose" either. There shouldn't even be a question about this.. it's so sad that in 2021 there are still people out there who question the right of a trans woman to use the female toilet.

In work we have one bathroom for everyone - never thought about it and nobody ever had an issue with that. In the fields I share with horses, cows, sheep, foxes and birds of all genders 🐮

Hey Fairre, yes that’s true but I just wanted to say that doctors are humans and not infallible. They have opinions too and they can be wrong. People should follow their hunch and get a second opinion if they’re not happy with the outcome of a visit or feel it has not addressed their issue. Docs do a lot of stupid things too but they’re not going to tell you that. Many drink a bit too much and smoke too, and also self medicate. Some go on trips with ready available drugs from the practice too, but they won’t tell their patients that either😀 So all I’m saying here is trust yourself first of all, you know your body better than anyone else and know what’s normal for you. I know what’s normal for all my pets, one of my horses always had a hot coronet band but that’s normal for him. It wouldn’t be normal for another one of my horses though. 😀

We don't need to uplift animals, as it has been demonstrated over and over again animals should uplift us humans.

Selene wait let me gather my cats, horses and dogs and hide them safely. Then Grandfather may nuke!

The thing about medical sciences is that they don't always get things right or hold absolute truths. There are some foundational science things we now (sometimes only sort of) understand like fundamental biochemistry, but the inner works of complex biological entities are still quite puzzling. The placebo effect for example does not make any sense. It's a whole lot of nothing and yet, sometimes it works. Years ago a group of scientists studied the effects of placebo (saline solution) on Parkinson's patients. The brain scans showed that there was reduced activity in single neurons on the placebo patients and that meant a great improvement on their condition. I will find the paper on pubmed, I just can't access it here at the moment. To this day it is not understood how a saline solution can improve Parkinson's disease, probably the neurons are "trained" to respond to the placebo who knows. When C19 hit the world hard doctors and scientists were trying to figure out what the hell was happening and how come there were so many different outcomes in patients that presented otherwise similar clinical profiles and parameters. When you are trying to save as many patients as you can (we do the same in veterinary medicine... it's tough to even lose one due to getting it wrong) and the world is looking at you expecting the miracle cure, well $hit happens and mistakes are made. They still tried to make sense of the data and tried whatever drugs were available that addressed that particular patient's profile and a lot of research stemmed from those initial trials (and errors). Monoclonal antibodies therapies (the ones Eli-Lilly made and regeneron for example), anti-IL6 (the ones that prevent cytokine storms) work in certain cases, not all and sometimes combined. Research is still ongoing and papers are churned out on a daily basis. Ivermectin is also something that is being explored -potentially- as its inventor (Prof. Campbell) said after reviewing the Australian study results last year. Why Ivermectin? Because this drug has proven anti-RNA viral properties for many viruses. So the reasoning was.. it might work for Covid. https://www.sciencedirect.com/science/article/pii/S0166354220302011 The issue here is that the Aussie studies were done in vitro, so they added the virus to a culture of cells on a petri dish. They then treated the infected culture with high doses of Ivermectin. What does "high doses" mean though? Normal dose to kill most parasites sensitive to Ivermectin is for humans 0.2 mg/Kg of body weight. For horses same, 0.2mg/Kg. What you work with here is concentration per dose given. After a normal dose of 0.2 mg/Kg of body weight the max concentration observed in the blood is typically 40 ng/ml. And that's where the problem is... did the Ivermectin kill the virus? Yes it did. What was the concentration to achieve a 50% reduction in viral replication? 2450 ng/ml. That's 60-times higher than the normal concentration at normal dosage. The highest dose ever given (other non-Covid related trails) is 0.8 mg/Kg Trials are ongoing but the issues here are a small number of volunteers and the potentially fatal high doses needed of Ivermectin to get results. I have a drawer full of EquiMax but I think I'll skip squirting some after my coffee for today!😅

Now now he’s just getting his highlights done 👌

I think when you clicked on the link that was the problem, and yes it sounds like you got hacked. The link ran a script and that’s how most people get hacked... they get conned into clicking malicious links. If you are concerned about your RL and these people made threats to you, gather all your evidence and report it to your local police. Most police departments nowadays have a cyber crime unit. Good luck hope you get this sorted.

That’s my understanding too! It’s turning into a cytokines storm in a teacup 😅☕️

Not for kitties though Love, you should stay away from salt! 🙀🦁

I'll stick around then! 😄🔥

Hopefully I haven't done anything so bad yet to be torched 🔥

I say that often and usually in reference to a certain species of bipedal animal 😄

Oops hey Maddy! 😄

That's a great analogy Madeleine, and just like you I never stop wondering at how complex and fabulous all living creatures are! The immune system of mammals is endlessly complex and I have just skimmed the surface of how it works. I am actually studying it in greater details at the moment for a specific set of equine metabolic diseases. I need immunology for dummies 🤣

The idea of treating C19 cytokine storms with antivirals or rheumatoid arthritis drugs came up last year while trying to figure out why some patients had awful outcomes after contracting COVID19 while others sailed through with a minor cold. The gravely ill ones presented a cytokine storm syndrome. The problem was to try and determine what kind of storm, as inflammatory responses produce certain signatures (the interleukins IL-s and CCRs). So as you correctly pointed out, the correct storm needs to be defined before the appropriate treatment is given. At the start of the pandemic it was noted that very ill patients presented elevated concentrations of IL-6. Leronlimab disrupts signaling to CCR5 receptors so in a way, it tells the immune system to stop recruiting T and macrophages (the inflamatory cells). In trials (out of desperation) ICU patients were given Leronlimab and that stopped the inflamatory process. The problem though is that in randomised studies it did not work as well. What worked better was giving patients IL-1 receptor antagonists. Tocilizumab also binds the IL-6 receptors and was also used in trials. I believe there are still trials in this area. I am not an immunologist, just a vet but immune systems are like biological machines and each one of us is tuned slightly different so responses to aggressors can be dramatically different in people that otherwise on the surface look perfectly similar. 🙂

All three and also gullible or just patsies

Large animal (cows, horses, pigs and sheep too) vet surgeon and horse livery yard owner 🐴

Thanks Layla only seeing this now, will add you when I get in-world! 🐎

Here's your builder's brew Lyndka 🙃

Thank you Rowan, I'll have a look at that

/waves / Haha I've been told the best Guiness is served from a tap, I can't comment as I don't like beer 😆 since we're all in lockdown, may I offer you all a cuppa instead?