IMO as Realistic as we can lol, closed minds don't get feed. Can only be as realistic as the tech allows. The main issue is lighting in engines it what really brings out everything cause of shadows and good ambient occlusion, global illumination and such. You can make some really realistic characters these days even for real time its not the problem, what makes character real is animations, realistic proportions for shape, beside that facial imperfections and skin pores getting use a lot closer pass that uncanny valley point as from what I'm seeing lately. If you want to look at some case studies of seeing what is possible look at TexturingXYZ, skin pores and face scans of color maps from real people, once someone has enough data of those can really create some insane character avatar systems. A normal map or displacement map of skin pores really changes alot and lighting of course. Just wanted to show people whats possible.
https://www.instagram.com/texturingxyz/
Heres a realtime character case study I found from Sefki Ibrahim, really cool stuff https://texturing.xyz/pages/realtime-digital-double-with-character-creator-and-texturingxyz-sefki-ibrahim