I've set my AVG to also block spyware. I never install extra toolbars, mouse pointers, themes and such. I use a very nice all in one maintenance utility from GlarySoft. I keep my hardrive partitioned will all my data (game saves, pictures, documents, chat logs, cache) on the second partition, keep Windows updated, I've doubled the virtual memory, disabled remote assistance, check every month for driver updates. Can't think of what else