In some cultures it is considered rude to ask about a person's health when meeting for the first time. Unless you really do want to hear about my health issues (most people don't, probably because they don't really care), don't ask. Don't put people who are not in good health or not feeling well in RL in that position. You're doing them more harm than good. In most cases, questions are a good thing. They show that you're actively engaged and interested in a conversation or experience.
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